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循環腫瘍DNAが早く消失してもアウトカムは変わらない

Clearing of circulating tumour DNA predicts clinical response to first line tyrosine kinase inhibitors in advanced epide…

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KEYNOTE-189 up date

Updated Analysis From KEYNOTE-189: Pembrolizumab or Placebo Plus Pemetrexed and Platinum for Previously Untreated Metast…

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根治治療後のフォローはどうすべきか?

Lung Cancer Surveillance After Definitive Curative-Intent Therapy: ASCO Guideline. Schneider BJ J Clin Oncol. 2020 Mar 1…

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クライオバイオプシーはEGFR遺伝子変異検出に有利?

Cryobiopsy increases the EGFR detection rate in non-small cell lung cancer. Haentschel M et al. Lung Cancer. 2020 Mar;14…

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TKI+ベバシズマブでT790Mが減る?

Investigation of efficacy and acquired resistance for EGFR-TKI plus bevacizumab as first-line treatment in patients with…

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中等度以上の自然気胸でもドレナージ不要

Conservative versus Interventional Treatment for Spontaneous Pneumothorax. Brown SGA et al. N Engl J Med. 2020 Jan 30;38…

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ALK-TKIはPD後もプラチナ+ペメトレキセドと併用した方がよい?

Efficacy of Platinum/Pemetrexed Combination Chemotherapy in ALK-Positive NSCLC Refractory to Second-Generation ALK Inhib…

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多発か肺内転移かの鑑別アルゴリズム

A Novel Algorithm to Differentiate Between Multiple Primary Lung Cancers and Intrapulmonary Metastasis in Multiple Lung …

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オシメルチニブ耐性、治療するほど多様化

Next-generation sequencing based mutation profiling reveals heterogeneity of clinical response and resistance to osimert…

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LCNECの治療は小細胞癌レジメンがbetter

Disparity in clinical outcomes between pure and combined pulmonary large-cell neuroendocrine carcinoma: A multi-center r…